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2000年以降の原著論文

S. Yasumoto, K. Tamura, J. Karasawa, R. Hasegawa, K. Ikeda, T. Yamamoto, H. Yamamoto. Inhibitory Effect of selective serotonin reuptake inhibitors on the vesicular monoamine transporter 2. Neurosci. Lett. 454, 229-232 (2009)

E. Fukuda, S. Hamada, S. Hasegawa, S. Katori, M. Sanbo, T. Miyakawa, T. Yamamoto, H. Yamamoto, T. Hirabayashi, T. Yagi. Down-regulation of protocadherin-alpha A isoforms in mice mice changes contextual fear conditioning and spatial working memory. Eur. J. Neurosci. 28, 1362-1376 (2008)

H. Yamamoto, E. Kamagaya, Y. Hagino, K. Imai, A. Fujikawa, K. Tamura, T. Enikiya, T. Yamamoto, T. Takeshima, H. Koga, G.R. Uhl, K. Ikeda, I. Sora. Genetic deletion of vesicular monoamine transporter-2 (VMAT-2) reduces dopamine transporter activity in mesencephalic neurons in primary culture. Neurochem. Int. in press (2007).

H. Yamamoto, K. Imai, E. Kamegaya, Y. Takamatsu, M. Irago, Y. Hagino, S. Kasai, K. Shimada, T. Yamamoto, I. Sora, H. Koga, K. Ikeda. Repeated methamphetamine administration alters expression of the NMDA receptor channel e4 subunit and kinesins in the mouse brain. Ann NY. Acad. Sci. 1074, 97-103 (2006).

A. Kakizaki, M. Takahashi, H. Akagi, E. Tachikawa, T. Yamamoto, E. Taira, T. Yamakuni, Y. Ohizumi. Ca2+ channel activating action of maitotoxin in cultured brainstem neurons. Eur. J. Pharmacol. 536, 223-231 (2006).

T. Yamamoto, K. Yuyama, H. Yamamoto. Low concentrations of nitric oxide (NO) induced cell death in PC12 cells through activation of p38 mitogen-activated protein kinase (p38 MAPK) but not via extracellular signal-regulated kinase (ERK1/2) or c-Jun N-terminal protein kinase (JNK). Neurosci. Lett. 392, 170-173 (2006).

A. Kakizaki, E. Tachikawa, T. Yamamoto, K. Takahashi, E. Taira, T. Yamakuni, Y. Ohizumi. Grayanotoxin III induces catecholamine secretion in bovine adrenal chromaffin cells but not PC12D cells. Pharmacometrics 69, 65-69 (2005).

A. Kakizaki, E. Tachikawa, T. Yamamoto, E. Taira, T. Yamakuni, Y. Ohizumi. Maitotoxin, palytoxin and grayanotoxin differentially elicit catecholamine secretion in cultured bovine adrenal chromaffin cells. Pharmacometrics 68, 145-151 (2005).

H. Yamamoto, K. Imai, Y. Takamatsu, E. Kamegaya, M. Kishida, Y. Hagaino, Y. Hara, K. Shimada, T. Yamamoto, I. Sora, H. Koga, K. Ikeda. Methamphetamine modulation of gene expression in the brain: Analysis using customized cDNA microarray system with the mouse homologues of KIAA genes. Mol. Brain Res. 137, 40-46 (2005).

H. Yamamoto, K. Imai, Y. Takamatsu, E. Kamegaya, Y. Hara, K. Shimada, T. Yamamoto, H-W. Shen, Y. Hagino, H. Kobayashi, S. Ide, I. Sora, H. Koga, K. Ikeda. Changes in expression of the mouse homologues of KIAA genes after subchronic methamphetamine treatment. Ann NY. Acad. Sci. 1025, 92-101 (2004).

H-W. Shen, Y. Hagino, H. Kobayashi, K. Shinohara-Tanaka, K. Ikeda, H. Yamamoto, T.  Yamamoto, K.P. Lesche, D. L. Murphy, F.S. Hall, G.R. Uhl, I. Sora. Regional differences in extracellular dopamine ans derotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonine transporters. Neuropsychopharmacol. 29, 1790-1799 (2004).

T. Yamamoto, I. Nishizaki, T. Nukada, E. Kamegaya, S. Furuya, Y. Hirabayashi, K. Ikeda, H. Hata, H. Kobayashi, I. Sora and H. Yamamoto. Functional identification of ASCT1 neutral amino acid transporter as the predominant system for the uptake of L-serine in rat neurons in primary culture. Neurosci. Res. 49, 101-111 (2004).

T. Yamamoto, I. Nishizaki, S. Furuya, Y. Hirabayashi, K. Takahashi, S. Okuyama and H. Yamamoto. Characterization of rapid and high affinity uptake of L-serine in neurons and astrocytes in primary culture. FEBS Letters 548, 69-73 (2003).

K. Yuyama, H. Yamamoto, I. Nishizaki, T. Kato, I. Sora and T. Yamamoto. Caspase-independent cell death by low concentrations of nitric oxide (NO) in PC12 cells: involvement of the inhibition of cytochrome c oxidase and the production of reactive oxygen species (ROS) in mitochondria. J. Neurosci. Res. 73, 351-363 (2003).

K. Yuyama, H. Yamamoto, K. Nakamura, I. Nishizaki, T. Yamakuni, Si-Y. Song, I Sora, T. Nagatsu, and T. Yamamoto. Overexpression of V-1 prevents nitric oxide-induced cell death: involvement of enhanced tetrahydrobiopterin (BH4) biosynthesis. J. Neurosci. Res. 72, 716-725 (2003).

T. Yamakuni, M. Hashimoto, H. Sakagami, T. Yamamoto, M. Kobayashi, Y. Fujii, H. Yamamoto, D.K. Rohra, T. Honma, H. Kondo, H. Shido, and Y. Ohizumi. Expression of V-1, a novel catecholamine biosynthesis regulatory protein, is enhanced by hypertention in atrial myocytes of Dahl salt-sensitive rats. Biochem. Biophys. Res. Commn. 298, 793-797 (2002)

T. Yamakuni, T. Yamamoto, Y. Ishida, H. Yamamoto, Si-Y. Song, E. Adachi, Y. Hiwatashi, and Y. Ohizumi. Enhancement of high potassium-induced catecholamine release in PC12 cell clones overexpressing V-1, a catecholamine biosynthesis regulatory protein. FEBS Letters 530, 94-98 (2002).

J. Karasawa, H. Yamamoto, T. Yamamoto, N. Sagi, K. Horikomi and I. Sora. MS-377, a selective sigma receptor ligand, indirectly blocks the action of PCP in the N-methyl-D-aspartate receptor ion-channel complex in primary cultured rat neuronal cells. Life Sci. 70, 1631-1642 (2002).

K. Yuyama, H. Yamamoto, K. Nakamura, T. Kato, I. Sora and T. Yamamoto. Resistance of PC12 cells against nitric oxide (NO)-induced toxicity in long-term culture: implication of neuronal NO synthase expression. Neurosci. Lett. 309, 169-172 (2001).

H. Yamamoto, J. Karasawa, N. Sagi, S. Takahashi, K. Horikomi, S. Okuyama, T. Nukada, I. Sora and T. Yamamoto. Multiple pathways of 1 receptor ligand uptakes into primary cultured neuronal cells. Eur. J. Pharmacol. 425, 1-9 (2001).

S. Furuya, T. Tabata, J. Mitoma, K. Yamada, M. Yamasaki, A. Makino, T. Yamamoto, M. Watanabe, M. Kano and Y. Hirabayashi. L-Serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons. Proc. Natl. Acad. Sci. USA, 97, 11528-11533 (2000).

T. Yamamoto, K. Yuyama, K. Nakamura, T. Kato and H. Yamamoto. Kinetic characterization of the nitric oxide toxicity for PC12 cells: effect of half-life time of NO release. Eur. J. Pharmacol. 397, 25-33 (2000)